Claudin 18.2 specific CART cells are giving a hopeful positive signal in digestive system tumors- supporting the use of CART in solid tumors #ESMO21 @CARsgen_Ther #immunotherapy #CARTcell https://www.prnewswire.com/news-releases/appealing-data-of-carsgen-therapeutics-car-t-ct041-in-advanced-gastric-cancer-presented-at-esmo-301380054.html
Great article about recent advances toward sickle cell disease cure âŠ@nytimesâ© âŠ@ginakolataâ© âŠ@nih_nhlbiâ© âŠ@GatesUSâ© âŠ@gateshealthâ© The time is now to develop low cost cures for all! âŠ@bluebirdbioâ© âŠ@ScottDRamseyâ© https://www.nytimes.com/2021/09/14/health/sickle-cell-cure.html
Wonderful summary from @PosAware of the @iasociety pre-conference on #HIV cure & #SickleCell disease https://www.positivelyaware.com/articles/highlights-2021-hiv-cure-and-gene-therapy-forum @globalgti
In 2020, the @globalgti was formed to tackle the barriers to #LMIC inclusion in #genetherapy development. We have set a goal of introducing two gene therapy Phase I #clinicaltrials in Uganda and India by 2024.
https://go.nature.com/3jXgr0p
Thrilled to share our 1st collaborative publication as the @globalgti working group:"Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI)" published in @GeneTherapy_SN. @cwru @CaseEngineer @fredhutch @caring_cross
https://www.nature.com/articles/s41434-021-00284-4
The highest prevalence of #HIV/#AIDS, #SickleCell and #thalassemia, and thus the populations who could benefit the most from one-time curative treatments (#genetherapy), are in low- and middle-income countries.
Read more in our @GeneTherapy_SN publication: https://www.nature.com/articles/s41434-021-00284-4
Great article summarizing #sicklecell advances! Gene therapies close in on a cure for sickle-cell disease https://www.nature.com/articles/d41586-021-02138-w
Spain is leading the way here in a distributed POC (point of care) model @CChabannon
Pr Alvaro Urbano-Ispizua (BCN) presenting the Spanish experience and projects with locally manufactured autologous CAR-T Cells to treat r/r ALL, NHL and MM at the 6th edition of âŠ@TheEBMTâ© ITC (virtual) âŠ@TheEBMT_CTIWPâ© âŠ@TheEBMT_Nursesâ© âŠ@JACIE_EBMTâ©
New pub highlighting efforts of Gates Fndtn & Novartis to bring curative cell/gene therapy for SCD & HIV âŠ@Novartisâ© âŠ@gatesfoundationâ© Collaborative science to advance gene therapies in resource-limited parts of the world: Molecular Therapy https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(21)00306-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1525001621003063%3Fshowall%3Dtrue
After a targeted #genetherapy operation at @OhioState to treat his #AADC, six-year-old Jamell no longer has seizures and is able to sit up and grab toys. #raredisease https://on.today.com/3zk28YL
The UK regulatory system is moving rapidly. Here is the link for âConsultation on Point of Care Manufacturingâ This framework should accelerate point of care manufacturing of cell and gene therapy products world-wide https://www.gov.uk/government/consultations/point-of-care-consultation/consultation-on-point-of-care-manufacturing
The UK is paving the way for âpoint of care manufacturingâ to bring the cost of cell and gene therapy down-by proposing a new regulatory approach @MHRAgovuk - We fully support this visionary approach! @ASGCTherapy @sitcancer @CRUK_Policy @AACR
Sickle cell disease is the most common cause of pediatric stroke.
Bonus tip: Stop saying "sickler"
